Buy Eugenol Liquid CAS 97-53-4 — Pharmaceutical & Fragrance Grade
Buy Eugenol Liquid CAS 97-53-4 — Pharmaceutical & Fragrance Grade
Eugenol is a naturally occurring phenylpropanoid
aromatic compound and one of the most important
and historically significant aroma chemicals in
global commerce. Found in high concentrations in
clove bud oil (72-90%), clove leaf oil, cinnamon
leaf oil, basil, and nutmeg, Eugenol has been used
in dentistry, perfumery, food flavouring, and
pharmaceutical synthesis for centuries. Today it
remains one of the most versatile and commercially
important specialty chemicals in international trade,
valued simultaneously across dental medicine,
fine fragrance, food flavouring, cosmetic formulation,
and pharmaceutical intermediate markets.
What makes Eugenol uniquely valuable is its
combination of powerful sensory character —
a warm, spicy, distinctive clove aroma — with
significant pharmacological activity including
local anaesthetic, antimicrobial, anti-inflammatory,
and antioxidant properties that have been
extensively documented in peer-reviewed literature.
This combination of olfactory and biological
activity across multiple high-value market
sectors makes Eugenol one of the most strategically
important aroma chemicals in industrial chemical supply.
Chemical Properties & Technical Specifications
CAS Number: 97-53-4
Other Names: 4-Allyl-2-methoxyphenol, Caryophyllic Acid,
Eugenic Acid, 2-Methoxy-4-(2-propenyl)phenol,
4-Allylguaiacol
Molecular Formula: C10H12O2
Molar Mass: 164.20 g/mol
Physical Form: Liquid
Appearance: Colourless to pale yellow oily liquid
(darkens to amber on air exposure)
Odour: Warm, spicy, powerful characteristic clove
aroma with woody and sweet undertones
Density: 1.064 - 1.070 g/cm3 at 20 deg C
Boiling Point: 254 deg C (489 deg F)
Melting Point: -9 deg C (16 deg F)
Flash Point: 110 deg C (230 deg F)
Vapour Pressure: 0.02 hPa at 20 deg C
Refractive Index: 1.540 - 1.542
Viscosity: 9.6 mPa.s at 20 deg C
Solubility: Slightly soluble in water (2.5 g/L at 20 deg C),
fully miscible with ethanol, chloroform,
and most organic solvents
Log Pow (octanol/water): 2.27
Purity: >=99.0% (pharmaceutical and fragrance grade)
FEMA Number: 2467
EINECS Number: 202-589-1
UN Number: Not classified as dangerous goods for
standard transport
Primary Applications
1. Dental and Oral Care
Eugenol is the most important active ingredient in
dental medicine, used extensively in dental cements,
impression materials, temporary filling materials,
root canal sealers, periodontal dressings, and dry
socket treatment formulations. Its local anaesthetic
properties provide effective pain relief in dental
procedures, while its antimicrobial activity inhibits
bacterial growth in dental applications. Zinc oxide
eugenol (ZOE) cement — formed by mixing eugenol with
zinc oxide powder — is one of the most widely used
dental materials in the world and is found in dental
clinics globally. This dental market represents one
of the largest and most consistent demand drivers
for pharmaceutical-grade Eugenol.
2. Fine Fragrance and Perfumery
Eugenol is a classic and irreplaceable material in
fine fragrance, contributing its warm, spicy, clove
character to oriental, floral-spicy, chypre, and
woody fragrance compositions. It is a key component
of carnation accords, spice accords, and oriental
base materials, and blends beautifully with isoeugenol,
cinnamic alcohol, geraniol, rose materials, musks,
and woody base notes. Its powerful odour intensity
means it is used at relatively low concentrations —
typically 0.1-2.0% — where it contributes significant
character to the overall composition. Eugenol also
serves as a chemical precursor for isoeugenol,
another important fragrance material.
3. Food and Beverage Flavouring
Eugenol is approved as a food flavouring agent
under FEMA GRAS status (FEMA 2467) and is used
in food and beverage products to contribute spicy,
clove-like flavour notes. Applications include
spice flavouring in confectionery, bakery products,
beverages, meat products, sauces, and condiments.
It is a key component of artificial clove, allspice,
and mixed spice flavour compositions used in the
food manufacturing industry.
4. Pharmaceutical Synthesis
Eugenol serves as an important starting material
and chemical intermediate in pharmaceutical
synthesis. Its phenylpropanoid structure and
allyl-methoxyphenol functionality provide a
versatile platform for chemical transformations
leading to bioactive pharmaceutical compounds.
Key synthesis applications include production
of isoeugenol (via isomerisation), vanillin
(via oxidation), and a range of pharmacologically
active derivatives investigated for antifungal,
antiviral, anticancer, and anti-inflammatory
pharmaceutical applications.
5. Cosmetic Formulation
Eugenol is used as a fragrance ingredient in
cosmetic and personal care formulations including
skincare, haircare, body care, and specialty
grooming products. Its warm spicy clove character
adds distinctive depth and masculinity to
fragrance compositions in aftershaves, beard
care products, and oriental-inspired personal
care formulations. Note: Eugenol is listed as
a fragrance allergen under EU Cosmetics Regulation
at concentrations above 0.01% in leave-on
products and 0.1% in rinse-off products —
labelling requirements apply in EU markets.
6. Antimicrobial and Preservative Applications
Eugenol's broad-spectrum antimicrobial activity
— documented against bacteria, fungi, and yeasts
including Staphylococcus aureus, E. coli,
Salmonella, Aspergillus, and Candida species —
makes it a candidate for natural preservative
and antimicrobial formulation applications.
Research interest in Eugenol as a natural
alternative to synthetic preservatives in
food, cosmetic, and pharmaceutical formulations
continues to grow, driven by clean label
and natural product trends.
7. Agricultural and Pest Control
Eugenol has demonstrated insecticidal and
repellent activity against a range of agricultural
pest insects and is used as an active ingredient
in natural insecticide and pest deterrent
formulations. Its natural origin and
biodegradability make it attractive in
organic and reduced-chemical agriculture
applications.
Order Information
Eugenol is available from UAB An Group Export in
the following configurations:
- Sample orders: 1L and 5L units — $170.00 per litre
- Bulk orders: 20L, 100L, and pallet quantities
- Custom volumes available on request
Contact us at info@angroupexport.com or via WhatsApp
at +1 (350) 210-1380 to request a quote.







