4-Chloronitrobenzene — CAS 100-00-5
4-Chloronitrobenzene — CAS 100-00-5
4-Chloronitrobenzene (p-CNB, CAS 100-00-5) is an aromatic halonitrile compound and a widely used chemical intermediate across dye, agrochemical, pharmaceutical, and specialty chemical manufacturing sectors. UAB An Group Export supplies it in technical and synthesis grades, matched to each customer's process and application requirements.
It is used primarily as a synthesis intermediate for the production of 4-nitroaniline, 4-chloroaniline, and related aromatic intermediates through selective reduction or nucleophilic substitution reactions — making it a core building block for downstream dye, agrochemical, and pharmaceutical synthesis. Its combination of an activating nitro group and a displaceable chloro leaving group gives it high synthetic versatility across nucleophilic aromatic substitution and reduction chemistry.
For qualified industrial buyers, supply is coordinated around grade, purity, volume, packaging, and delivery destination, in line with applicable product, handling, and regulatory requirements. Bulk and commercial orders are both handled — send your requirements and we'll prepare a quote covering supply, packaging, logistics, and delivery.
Regulatory Notice — Carcinogen Classification
4-Chloronitrobenzene is classified as a Category 2 suspected carcinogen under EU GHS/CLP Regulation (H351). It is also toxic by ingestion, skin absorption, and inhalation, and can cause methemoglobinemia on systemic exposure. Buyers are responsible for ensuring compliance with all applicable occupational health and safety regulations, carcinogen handling requirements, and environmental regulations in their jurisdiction. Refer to the SDS for full hazard information, PPE requirements, and exposure control measures. This product is supplied for qualified industrial and synthesis applications only.
Key Applications
Dye & Pigment Intermediate SynthesisA primary intermediate in the production of 4-nitroaniline (via ammonolysis) and 4-chloroaniline (via catalytic reduction) — both widely used building blocks in azo dye, disperse dye, and pigment manufacturing for textile and industrial applications.
Agrochemical ManufacturingUsed as a synthesis intermediate in the production of select herbicides, fungicides, and other agrochemical active ingredients requiring a chloronitrobenzene scaffold.
Pharmaceutical Intermediate SynthesisUsed as a building block in the synthesis of select pharmaceutical active ingredients and intermediates through nucleophilic aromatic substitution and reduction chemistry.
Rubber Processing ChemicalsUsed as an intermediate in the synthesis of select rubber processing chemicals and antioxidants.
Specialty Chemical SynthesisUsed across a range of specialty chemical synthesis applications requiring a halogenated nitroaromatic starting material for selective functionalization reactions.
Supply & Packaging
Supplied according to your required grade and purity, quantity, packaging, and destination. 4-Chloronitrobenzene is a pale yellow crystalline solid at room temperature with a characteristic aromatic odor and a melting point of approximately 83–84°C. As a toxic solid classified as a suspected carcinogen (UN 1578, Class 6.1, PG III), packaging, transport, and handling are arranged according to applicable dangerous-goods requirements, typically in sealed, moisture-proof drums or bags with appropriate hazmat labeling and documentation.
Storage must be in sealed containers away from heat, light, reducing agents, and incompatible materials. Given its carcinogen classification, dedicated storage segregated from food, feed, and pharmaceutical materials is required. Skin contact and inhalation must be strictly avoided — appropriate PPE including chemical-resistant gloves, eye protection, full face shield, and respiratory protection is mandatory during all handling operations.
Product Documentation
Available on request, depending on the specific product and supply arrangement:
Safety Data Sheet (SDS), including carcinogen classification, methemoglobinemia risk, and full PPE requirements
Certificate of Analysis (CoA), including purity, melting point, and color specification
Technical Data Sheet (TDS)
Product specifications
Dangerous goods declaration
Shipping and transport documentation
Compliance statement:
"Due to the hazard classification of this product as a Category 2 suspected carcinogen, all orders are subject to business registration verification and end-use declaration prior to confirmation. Buyers are responsible for verifying that the intended end use and market application comply with all applicable carcinogen handling regulations, occupational health and safety requirements, environmental regulations, and dangerous-goods handling obligations in their jurisdiction. UAB An Group Export reserves the right to request additional end-use declarations or supporting documentation and to decline any order where end use, destination, or buyer information cannot be adequately confirmed."
Request a Quote
Whether you need 4-chloronitrobenzene for dye intermediate synthesis, agrochemical manufacturing, pharmaceutical intermediates, or another qualified industrial synthesis purpose, provide your requirements and our team will review the available supply options.
For a quotation, please provide: company name and registration → end-use application and downstream product → required grade and purity → quantity → packaging → delivery country/city or port → required delivery timeframe